Small artery prognosis and tre

Time: October 30, 16:10-16:30 location: Hall 5 small structural changes can be seen as resistance hypertension and ischemic heart disease, heart failure, ischemic attack and a critical link between renal failure. Generally agreed that resistance vessel structural abnormalities are common changes associated with chronic hypertension. Vessel wall thickness increases, together with smaller lumen may play an important role in the increased vascular resistance may also be increased hemodynamic load an adaptive response. Experimental study showed that small artery structural changes are normal thickness in hypertensive remodeling or reconstruction of hypertrophic (narrow the lumen same number around rearrange or smooth muscle cell hypertrophy of vascular wall material or proliferation) consequences. Vascular membrane and increase in the ratio of the lumen is of primary and secondary hypertension risk population in strong predictors of cardiovascular events. Recently, the subcutaneous prognostic significance of small resistance artery structural changes have been extended to any low to essential hypertension and cardiovascular risk of major cardiovascular events (myocardial infarction, stroke and sudden death). Research shows that after diludin calcium channel blockers, angiotensin-converting enzyme inhibitors and angiotensin receptor blockers in long-term effective treatment, small resistance vessel structure is likely to return fully to normal.　However, reverse vascular prognostic effect of structural changes is still not clear, there is need for trauma small prospective study, to clarify its role as antihypertensive treatment evaluate alternative end of May.